By Perminder Sachdev
This quantity presents the 1st finished account of the clinical and scientific elements of akathisia and comparable syndromes equivalent to stressed legs syndrome (RLS), other kinds of motor restlessness, and neuroleptic-induced dysphoria. the main target is on drug-induced akathisia and its numerous subtypes. the writer explores its courting to the restlessness brought on by different neurological issues, provides a brand new synthesis of the pathophysiological mechanisms of akathisia, and gives arguments for brand spanking new operational standards for the study analysis of drug-induced akathisia. ideas for the dimension of akathisia also are mentioned, as are remedy methods. The booklet may be rather beneficial for psychiatrists, neurologists, and different physicians looking a greater figuring out of those disabling syndromes.
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Extra info for Akathisia and Restless Legs
Item definitions: Behaviours rated on 3point scale of frequency or severity, depending on the individual item; overall impression rated on 5-point scale of severity for each category. Psychometric validity: Face validity high. Reliability: Interrater reliability high. Comments: Recognized by WHO; however, more validity and reliability studies are required, as is a manual for the scale. 2. Fidgeting a. Fidgeting Tendency Questionnaire (Mehrabian and Friedman, 1986). Type: Behavioural scale. Subject area: Fidgeting tendency.
The clinical impor- Akathisia: development of the concept 17 tance of at least two disorders that it has been used to describe - drug-induced akathisia and RLS - is beyond dispute. Yet akathisia has remained the Cinderella of psychiatric research until recently (Stahl, 1985). This book is an attempt to synthesize the current information on this syndrome and remedy its neglect. The anatomy of restlessness Restlessness: aimless activity, pottering, desultoriness, inattention, unquiet, fidgets, fidgetiness, agitation, fever, fret, frenzy, eagerness, enthusiasm, ardour, abandon, warm feeling, vigour, energy, dynamism, aggressiveness, militancy, enterprise, initiative, push, drive, ego, pep, vigorousness, watchfulness, vigilance, carefulness, wakefulness, sleeplessness, insomnia.
Doses that produce altered consciousness (delirium) are not included as evidence. calcium channel antagonists, etc. (Sachdev and Loneragan, 1991a). Tricyclic antidepressants have been reported to cause restlessness in panic disorder patients, a syndrome that has been referred to as 'jitteriness' (Beasley et al, 1993). Some tricyclic drugs (eg, amoxapine) have an intrinsic dopamine antagonist property which may explain tricyclic-induced akathisia, but akathisia has also been reported in patients treated with tricyclics and oestrogen (Krishnan et al, 1984).
Akathisia and Restless Legs by Perminder Sachdev